Moderate alcohol consumption linked to reduced coronary heart disease risk in earlier studies. Up to one drink per day for women and two for men defined moderate consumption. Early 2000s research suggested moderate wine intake increased HDL cholesterol levels. Medical professionals call HDL cholesterol the "good" cholesterol for cardiovascular health. Moderate wine consumption lowered clot formation according to research findings. Some observational studies reported 20-30% cardiovascular mortality reduction among moderate drinkers. Non-drinkers showed higher mortality compared to those consuming alcohol moderately.